Started by checking out the origins of quinine and artemisinin online. Both were 'discovered' by local folk using them naturally hundreds of years ago, then rediscovered and sold in more deliberate forms.
Moved on to sickle cell where as one would expect, people have tried going into the stem cells for red-blood cell production and switching the one mutated point in patient's DNA right back.
|Read from bottom to top|
Read about the wide variation in how rough people with this genetic disease have it: from not-so-bad in many of the Arabian occurrences to regular killer in Africa.
|I don't really like twitter but yeah I'm @tosinbird|
But lots of questions still - remember the prophylactic 'Sunday-Sunday medicine' we used to take for malaria in boarding school - what was that about?
What other cool manipulations can prevent the occurrence of sickle-cell and its related suffering? Nowadays we tell people that 'AS shouldn't marry AS, only marry AA' but how easy is that to understand? And for those who understand it, I've seen how painful it can be for a young couple to have to break off their engagement after a drug test says they're both AS. More than 20% of Nigerians are either AS or SS according to this paper.